Could medications contribute to Dementia?

Alzheimer’s disease and other illnesses that cause dementia is devastating, not only for those affected but also for their friends and family. For example, available treatments for Alzheimer’s disease may slow the deterioration a bit, but they don’t reverse the condition. In fact, for most people taking medications for dementia, it might be hard to know whether the treatment is working by any means.

Dementia will turn out to be significantly more typical in the coming years. We severely need a superior comprehension of the reason for these conditions, as this could prompt better medications and even preventive measures. The focal point of this examination was on drugs with "anticholinergic" impacts. These are drugs that hinder a substance flag-bearer called acetylcholine, which influences muscle movement in the stomach related and urinary tracts, lungs, and somewhere else in the body. It's additionally engaged with memory and learning.

Common examples include:

·         amitriptyline, paroxetine, and bupropion (most normally taken for dejection)

·         oxybutynin and tolterodine (taken for an overactive bladder)

·         diphenhydramine (a typical antihistamine, as found in Benadryl)

So, should you be worried about your medications and dementia?

These findings are intriguing, but they aren’t definitive, and they don’t mean you should stop taking a medication because you’re concerned about developing dementia.

Medications were more common in people later diagnosed with dementia. That doesn’t mean these drugs caused dementia. There are other potential explanations for the findings. For instance, a few people create dejection amid the early periods of dementia. Instead of antidepressants causing dementia, the medication may be recommended for early side effects of dementia that has officially created. This is called “confounding by indication” and it’s a potential flaw of studies like this one that attempts to link past medication use with the future disease.

Acetylcholine is involved in memory and learning, and past research has demonstrated lower levels of acetylcholine in the brains of people with Alzheimer’s disease (the most common cause of dementia in the elderly). Moreover, the creature thinks about to recommend that anticholinergic medications may add to mind irritation, a potential supporter of dementia.

This recent research linking certain medications with dementia risk reminds us that the risks of some medications are only uncovered years after their use becomes commonplace.

Contact Details:

Cassandra Wilson

Program Manager | Dementia Conference 2019

Email: dementia@neurologymeet.org

dementiameet@neuroconferences.com

Tel No: +44-2088190774