Monday, May 6, 2019

PARKINSON’S DISEASE


Parkinson's disease is a neurodegenerative disorder that affects predominately dopamine-producing “dopaminergic” neurons in a specific area of the brain called substantia nigra. Parkinson's disease is a progressive nervous system disorder that affects the movement. Symptoms start gradually with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of the movement.

Symptoms:
Tremor: A tremor or shaking is usually begins in a limb, often your hand or fingers. You may a rub your thumb and forefinger back-and-forth, known as a pill-rolling tremor. Your hand may tremor when it's at rest.

Slowed movement (Bradykinesia): Parkinson's disease may slow your movement, making simple tasks difficult and time-consuming. Your steps may become shorter when you walk. It may be difficult to get out of a chair. You may graft your feet as you try to walk.

Rigid muscles:  Muscle stiffness may occur in any part of your body. The stiff muscles can be painful and limit your range of movement.

Impaired posture and balance: Your posture may become curved or you may have balance difficulties as a result of Parkinson's disease.

Loss of automatic movements: You may have a reduced ability to achieve unconscious movements, including blinking, smiling or swinging your arms when you walk.

Speech changes: You may speak softly, quickly, smear or hesitate before talking. Your speech is more of a monotone rather than with the usual modulations.

Writing changes: May be it’s become hard to write and your writing may appear small.

Conclusion:
There is no cure for Parkinson's disease, but medications, surgery, and physical treatment can provide relief and are much more effective than treatments available for other neurological disorders like Alzheimer’s disease, motor neuron disease, and Parkinson plus syndromes. The main families of the levodopa drugs are useful for the treating motor symptoms.

Exercise in the middle age may reduce the risk of Parkinson's disease later in the life. Caffeine also seems protective with a greater decrease in the risk occurring with a larger intake of caffeinated beverages such as coffee.

Thursday, March 14, 2019

Resisting Dementia: How to Keep Your Brain Fighting Fit

DEMENTIA isn’t inevitable. The human brain can stay shrill well past 100 years of life. Yes, receiving older decelerates us down and brain parts are associated with memory and administrative function shrink, myelin sheaths around our neurons start to erode, slowing down signalling, and arteries narrow retreating blood supply. But those things mainly will affect the speed, when healthy and an older people are given an extra time to perform cognitive tasks, the results are on par with younger folks.
                             
The number of people affected by dementia may be increasing, but most experts say that’s generally because more of us are living longer. Between the late 1980s and 2011, the proportion of people over 65 with dementia actually fallen by 20% in England and Wales. Between 2000 and 2012, dementia rates in that age group dropped by 24% in the USSimilar declines have been reported in other developed countries. There are two driving factors, says Kenneth Lange at the Michigan Centre on the Demography of Aging, who tracked the US trend: a rise in educational attainment and better control of cardiovascular issues. After the Second World War, there was an upturn in schooling that averaged out to about an extra year of education across the US population.


Exploration will suggest that people with more education, or those who have done things like acquire a new language or learn to play a musical instrument, may be resilient to signs of dementia. It doesn’t mean that they will escape the ravages of vascular dementia or plaques of Alzheimer’s, but they may handle better with the brain damage. “By stimulating your brain throughout education, you can generate a more fitness to the brain, that can recompense for difficulties that you have as your age”. Inflated cognitive reserve is thought to help in two ways: one is boosting the brain’s ability to work around damaged areas, and the second one is to promote more efficient processing of the brain. .
In disparity, dementia alters the cognitive playing field. As well as affecting memory, it causes issues with understanding or expressing oneself in language, problems with sensory perception, and disturbances in executive function that can undermine day-to-day independence. Aging are eager to find ways to maintain brain health and remain independent as long as possible. It's becoming clearer that simple lifestyle changes "can cause new areas of your brain to be used to prolong brain health and maybe stave off dementia,"
5 ways to keep Brain sharp and fight for dementia
·      Keep moving: Increased physical exercise was one of only three actions that provide "encouraging, although inconclusive" and it will benefits in preventing cognitive decline and dementia.
·         Eat well: Healthy food choices may reduce inflammation, which is linked to cognitive decline, and improve blood flow, which affects brain health.  
·         Learn something new: One of the most important and newest research findings is that people with more formal education have a lower incidence of Alzheimer's or dementia,"
·         Get a social life: Socializing with others keeps the brain healthy and may ward off dementia by strengthening connections between neurons. Invest in social activities important to you, such as joining a band or volunteering at the library.
·         Catch some Sleep: Sleeping less than seven or eight hours a night is linked to cognitive decline, memory loss and possibly Alzheimer's



Friday, February 22, 2019

Dizziness Could Be A Sign of Dementia Risk?


Are you a middle-aged person who tends to feel a little woozy when you stand up?


If so, you might need to worry more about developing dementia later in life. where pulse drops forcefully when an individual stands up rapidly. That can trigger sudden side effects like unsteadiness, dazedness, and blurry vision.

The condition is basic in old individuals influencing around 30 percent of those matured 70 and more seasoned, in view of an ongoing report. It is substantially less predominant in more youthful grown-ups, however when it occurs there is cause for concern. moderately aged individuals with the circulatory strain condition were 54 percent bound to create dementia throughout the following 25 years, versus those without the condition.


Health conditions influencing the veins including hypertension and diabetes are additionally connected to a higher danger of dementia. individuals who feel dizzy when they stand up from resting or sitting positions are more in danger of creating dementia or stroke.  


Relatively younger people the condition could be a sign of generally poorer health and greater medication use. Many medications for high blood pressure and other conditions can cause these drops in blood pressure.


People with orthostatic hypotension were relatively older and had higher rates of high blood pressure and diabetes. But even after it was still linked to a greater risk of developing dementia.


People do not always notice the symptoms, it was detected through blood pressure tests. How many people were actually experiencing these symptoms in their daily lives? 

Cassandra Wilson
Program Manager | Dementia Conference 2019
Tel No: +44-2088190774

Friday, February 15, 2019

Could medications contribute to Dementia?



Alzheimer’s disease and other illnesses that cause dementia is devastating, not only for those affected but also for their friends and family. For example, available treatments for Alzheimer’s disease may slow the deterioration a bit, but they don’t reverse the condition. In fact, for most people taking medications for dementia, it might be hard to know whether the treatment is working by any means.

Dementia will turn out to be significantly more typical in the coming years. We severely need a superior comprehension of the reason for these conditions, as this could prompt better medications and even preventive measures. The focal point of this examination was on drugs with "anticholinergic" impacts. These are drugs that hinder a substance flag-bearer called acetylcholine, which influences muscle movement in the stomach related and urinary tracts, lungs, and somewhere else in the body. It's additionally engaged with memory and learning.

Common examples include:
·         amitriptyline, paroxetine, and bupropion (most normally taken for dejection)

·         oxybutynin and tolterodine (taken for an overactive bladder)

·         diphenhydramine (a typical antihistamine, as found in Benadryl)

So, should you be worried about your medications and dementia?

These findings are intriguing, but they aren’t definitive, and they don’t mean you should stop taking a medication because you’re concerned about developing dementia.


Medications were more common in people later diagnosed with dementia. That doesn’t mean these drugs caused dementia. There are other potential explanations for the findings. For instance, a few people create dejection amid the early periods of dementia. Instead of antidepressants causing dementia, the medication may be recommended for early side effects of dementia that has officially created. This is called “confounding by indication” and it’s a potential flaw of studies like this one that attempts to link past medication use with the future disease.
Acetylcholine is involved in memory and learning, and past research has demonstrated lower levels of acetylcholine in the brains of people with Alzheimer’s disease (the most common cause of dementia in the elderly). Moreover, the creature thinks about to recommend that anticholinergic medications may add to mind irritation, a potential supporter of dementia.
This recent research linking certain medications with dementia risk reminds us that the risks of some medications are only uncovered years after their use becomes commonplace.

Cassandra Wilson
Program Manager | Dementia Conference 2019
Tel No: +44-2088190774


Friday, February 1, 2019

Dementia in Children: Yes! Children suffer from it, too!!

          Dementia in Children: Yes! Children suffer from it, too!!




When you hear the word dementia, you presumably connect it with older individuals. As we age, our subjective capacities bit by bit decline, influencing us to overlook things or feel confounded. Although this is normal with maturity if the side effects seem more awful than what's viewed as ordinary, every one of the bolts points towards dementia. In any case, isn't this just for the older? The danger of kids procuring this horrible infection is genuine. A few kids may give off an impression of being totally solid, however, their psyche may not be working regularly.

The symptoms

Most scatter that reason dementia among youngsters are uncommon and terminal. It is basic to distinguish the side effects at an early stage so appropriate restorative consideration and support are given to the kid. The pointers of youth dementia vary exclusively, contingent upon the sort and reason for dementia. Be that as it may, there are some basic side effects

Memory loss

A standout amongst the most well-known side effects of dementia in kids is memory misfortune. We overlook things every now and then. Nonetheless, if your youngster is overlooking things more much of the time or asking similar inquiries more than once, it could be a sign of dementia.

Memory misfortune alone does not imply that your tyke has dementia. To make a total analysis, specialists scan for something like two impeded subjective capacities that are available without loss of cognizance.

Problems with language

Kids with dementia may have trouble assembling words and trouble with expressive and responsive dialect aptitudes all in all. You may see variations from the norm in both verbal and non-verbal correspondence. 


Loss of intellectual skills

Youngsters experiencing dementia can show an absence of critical thinking capacity. Since the manifestations of dementia are commonly dynamic in nature, the hindrance of the scholarly capacity progressively compounds after some time. This can prompt a failure to adapt to new things.

Personality changes

Most kids with dementia experience conduct change through the span of the ailment, these progressions including:

·         Emotional episodes and absence of enthusiastic control
·         Showing tension, outrage, and uneasiness
·         Disarray about individuals and spots
·         Shouting and crying regularly
·         The absence of individual cleanliness
·         Awkwardness

 Dealing with dementia in children

The treatment of dementia relies upon its motivation. Most kinds of dynamic dementias don't have any fix and there is no real way to back off its movement. Be that as it may, there are sorts of medicines accessible to help enhance the manifestations of dementia.
Understanding the indications in detail and decreasing or taking out the triggers can deal with the conduct issues related to dementia.


Cassandra Wilson
Program Manager | Dementia Conference 2019
47 Churchfield Road
London, W3 6AY, UK
Tel No: +44-2088190774

Monday, January 28, 2019

Depression expands the danger of dementia by 40%.




Depression expands an individual's danger of dementia by 40%, paying little respect to sexual orientation, race, ethnicity, training or whether the individual has ordinary social contact with loved ones. That is as per recently discharged aftereffects of an examination including information gathered more than 10 years from 12,000 individuals.

"We are not the principal individuals to demonstrate that dejection is related with the expanded danger of dementia," But this is by a long shot the biggest example yet, with a long development. What's more, the populace was progressively different."

in which members matured at least 50 years, and their life partners, gave an account of their dejection and furthermore experienced a battery of subjective tests at regular intervals, up to 10 years after their reports of forlornness.

Throughout the examination, dementia created in 1,104 members. Members who detailed more prominent sentiments of dejection were bound to create dementia throughout the following 10 years.

The group characterized dejection as "the emotional experience of social separation," which is unique in relation to genuine social disengagement.

"It's an inclination that you don't fit in or don't have a place with the general population around you,". "You can have someone who lives alone, who doesn't have particularly contact with individuals, however, has enough — and that fills their inner requirement for mingling. So, despite the fact that impartially you may imagine that individual is socially separated, they don't feel desolate.

"The other side is that you can be around many individuals and be socially connected with an intelligent and still feel like you don't have a place," she included. "All things considered, it would appear that you have an extraordinary social commitment, yet the emotional inclination is that you're not part of the gathering."

"loans validity to getting some information about things — for this situation, how they feel about their social connections." fortunately forlornness is a modifiable hazard factor.


Contact Details:
Cassandra Wilson
 Program Manager-Dementia Conference 2019
 Email: dementia@neurologymeet.org


Friday, January 18, 2019

Cerebrum changes associated with alzheimer's disease


A Sound grown-up mind has around 100 billion neurons, each with long, expanding augmentations. These augmentations empower singular neurons to shape associations with different neurons. At such associations, called neurotransmitters, data streams in little blasts of synthetics that are discharged by one neuron and distinguished by a getting neuron. The mind contains around 100 trillion neural connections.

They enable signs to travel quickly through the cerebrum's neuronal circuits, making a cell premise of recollections, considerations, sensations, feelings, developments and aptitudes. The gathering of the protein part beta-amyloid (called beta-amyloid plaques) outside neurons and the collection of an unusual type of the protein tau (called tau tangles) inside neurons are two of a few cerebrum changes related with Alzheimer's. Beta-amyloid plaques are accepted to add to cell passing by meddling with neuron-to-neuron correspondence at neurotransmitters, while tau tangles hinder the vehicle of supplements and other fundamental atoms inside neurons.

As the measure of beta-amyloid expands, a tipping point is come to at which unusual tau spreads all through the brain. Other cerebrum changes incorporate aggravation and decay. The nearness of poisonous beta-amyloid and tau proteins actuates invulnerable framework cells in the mind called microglia. Microglia endeavor to clear the harmful proteins just as across the board flotsam and jetsam from dead and biting the dust cells. Incessant aggravation is accepted to set in when the microglia can't stay aware of such should be cleared. Decay, or shrinkage, of the mind, happens due to cell misfortune. Ordinary cerebrum work is additionally imperiled by the diminished capacity of the mind to process glucose, its principle fuel.


The research proposes that the mind changes related to Alzheimer's may start at least 20 years before indications appear. When the underlying changes happen, the cerebrum adjusts for them, empowering people to keep on working ordinarily. As Neurological Diseases harm builds, the cerebrum can never again make up for the progressions and people demonstrate unpretentious intellectual decay. Afterward, neuronal harm is significant to the point that people demonstrate evident subjective decrease, including indications, for example, memory misfortune or perplexity as to time or place. Even later, essential real capacities, for example, gulping are weakened. While inquiring about settings have the instruments and skill to recognize a portion of the early mind changes of Alzheimer's, extra research is expected to tweak the apparatuses' precision before they end up accessible for clinical use. 

Contact details: